Non-Invasive Stimulation for Alzheimer’s

By Rebecca Bartoli | July 31, 2024

In this insightful episode of Research Renaissance, Dr. Alexandra Touroutoglou shares her extensive work on brain imaging and non-invasive brain stimulation techniques to treat Alzheimer’s disease and related dementias. Discover the cutting-edge technologies and methods being employed to understand and combat neurodegenerative diseases.
Key Points Discussed:
• Academic Journey:
◦ Dr. Touroutoglou’s transition from studying in Greece to pioneering neuroscience research at Harvard, highlighting the expansive possibilities in U.S. science.
• Non-Invasive Brain Stimulation:
◦ Exploration of transcranial magnetic stimulation (TMS) and its role in inducing neuroplasticity, potentially reversing the effects of brain atrophy in Alzheimer’s patients.
• Integration of Brain Imaging:
◦ The use of advanced MRI techniques to diagnose and understand Alzheimer’s at a granular level, aiding the precise application of TMS.
• Clinical Trials and Promising Results:
◦ Insights into ongoing clinical trials started in 2019, showing promising preliminary results in improving symptoms of Alzheimer’s through innovative stimulation methods.
• Super Agers Study:
◦ Discussion of a 2016 study identifying “super agers,” older adults whose brains exhibit minimal signs of aging, providing clues into combating neurodegenerative diseases.
• Future Technologies:
◦ The potential impacts of artificial intelligence and machine learning in enhancing diagnostic accuracy and treatment personalization.
• Global Collaboration:
◦ The importance of interdisciplinary and international cooperation in advancing Alzheimer’s research, with a nod to Dr. Touroutoglou’s efforts to foster connections with Greek scientists.

To dive deeper into Dr. Touroutoglou’s research or participate in clinical trials, visit the Harvard Catalyst website or the Frontotemporal Dementia Unit at Massachusetts General Hospital.

Join us as we continue to explore groundbreaking advancements in brain science and strive towards innovative treatments for neurological diseases. For more episodes and information, subscribe to our podcast and visit tofflertrust.org. Feel free to reach out with thoughts, suggestions, or to learn more about the Karen Toffler Charitable Trust.